ncRNA name | VEGFA shRNA |
ncRNA Category | shRNA |
Disease name | retinopathy of prematurity (ROP) |
Species | Homo sapiens |
Tissues/Cell_line | human primary retinal microvascular endothelial cells (hRMVECs) |
Methods | shRNA knockdown, qPCR, ELISA, Western blot |
Expression pattern | associated |
Functional description | Targeted knockdown of overexpressed VEGFA in Muller cells safely reduces IVNV in a relevant ROP model. |
PubMed ID | 23972394 |
Year | 2013 |
Title | Short hairpin RNA-mediated knockdown of VEGFA in Müller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity. |
Drug-related ncRNA | NA |
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