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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinopathy of prematurity (ROP)
ncRNA name VEGFA shRNA
ncRNA Category shRNA
Disease name retinopathy of prematurity (ROP)
Species Homo sapiens
Tissues/Cell_line human primary retinal microvascular endothelial cells (hRMVECs)
Methods shRNA knockdown, qPCR, ELISA, Western blot
Expression pattern associated
Functional description Targeted knockdown of overexpressed VEGFA in Muller cells safely reduces IVNV in a relevant ROP model.
PubMed ID 23972394
Year 2013
Title Short hairpin RNA-mediated knockdown of VEGFA in Müller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity.
Drug-related ncRNA NA

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